<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10IV, I13V, I15V, K20I, E35K, M36I, R41N, K45R, L63P, C67S, H69K, L89M  
>ZZR468| codons 1-99
PQITLWQRPVVTVKVGGQLIEALLDTGADDTVLEKINLPGNWKPRMIGGIGGFIKVRQYD
QIPIEISGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M, M184V A62AV, V75VI, F77FL, K219Q Y181C V108I K20R, V35T, E36D, T39A, K43E, K49R, K64R, K122E, I135V, S162A, E169EA, K173A, Q174K, N175Y, D177E, T200A, Q207E, H221Y, L228LR, V245Q, E248D, K281R, E291D, I293V, P294T, S322T, I329V  
>ZZR468| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTDICAEMEEEGKISRIGPENPYNTPV
FVIRKKDSTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQASMTKILAPFRAKYPEIVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDQKYQKEPPFRWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEVQKQGQ

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009