<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KR, M184V, T215F K219KQ K103N A98G K20R, V35T, V60I, S68SG, D123E, I135T, S162A, K173T, Q174A, D177E, G196E, T200A, Q207G, R211K, F214L, V245Q, E248D, A272P, L283I, T286A, E291D, V292I, I293V, S322T  
>ZZR351| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNGTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTANPEIVI
YQYVDDLYVGSDLEIEQHRAKIEELRGHLLKWGLFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G17E, K20I, M36L, R41K, K43R, L63T, I64M, H69K, K70R, L89M  
>ZZR351| codons 1-99
PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEELNLPGKWRPKMIGGIGGFIKVRQYD
QITMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009