<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|TDF|D4T|AZT|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M, M184V V75VA, F77FL Y181C V179E V35T, T39TAS, E40ED, S68G, A98S, I135L, K173T, D177E, I178M, T200A, Q207X, L210M, R211AEKT, F214FL, V245Q, E248N, D250E, A272P, T286A, V292VI, I293V, E297K, A304E, K311R, I329V  
>ZZQ982| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICSDMEKEGKISKIGPENPYNTPV
FAIKRKDGTKWRKLADLRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTQNPEMEI
CQYVDDLYVGSDLEIGQHRAKIEELRXHLMTWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTKEAE
LELEENREILREPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20I, E35Q, M36I, R41K, K45R, R57K, L63AS, C67E, H69K, V82I, L89M  
>ZZQ982| codons 1-99
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPRMIGGIGGFIKVKQYD
QISIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009