<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13V, K14R, I15V, K20I, M36I, N37D, R41K, L63S, I64M, H69K, K70R, L89M  
>ZZR216| codons 1-99
PQITLWQRPLVAVRVGGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QISMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115YF, M184V   K103N, Y181C   P4PS, E28A, V35T, E36D, V60I, I135V, T139TA, S162A, K173A, Q174K, D177E, T200A, Q207E, R211RK, F214L, H221Y, L228LH, V245Q, A272G, L283I, T286A, V292I, I293V, S322T, I326V  
>ZZR216| codons 1-334
PISSIETVPVKLKPGMDGPKVKQWPLTAEKIKALTDICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAFFSVPL
DKDFRKYTAFTIPSVNNEAPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKYQKEPPFHWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYGGIKVKQLCKLIRGAKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009