Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|D4T|NVP|EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, E35Q, M36I, R41K, R57K, L63A, C67E, H69R, V82I, L89M |
| >ZZR5| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD QIAIEIEGRKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MIV | K103N, Y181C | V108VI | K20KR, V35T, T69S, W88C, K122E, I142V, F171Y, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, V245Q, E248D, D250E, S251DN, A272P, Q278H, T286A, E291D, I293V, P294PS, E297T, L301M, I329V | V292R |
| >ZZR5| codons 1-333 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPYRAKNPEMVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPDKENWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDRVSLTTEAE MELAENREILKEPVHGVYYDPSKDLIAEVQKQG |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |