<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10M, V11A, I13V, K14R, K20I, E35Q, M36I, N37DE, R57K, C67E, H69K, V82I, L89M  
>ZZR48| codons 1-99
PQITLWQRPMATVRIGGQLIEALLDTGADDTVLEQIELPGRWKPKMIGGIGGFIKVKQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, K70R, M184V, T215F K219Q V106A, G190GA F227L V35T, V60I, W88C, A98S, K122E, D123G, E138A, I142IV, K173T, Q174R, D177E, I178L, T200A, I202IV, R211K, F214L, H221HY, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, S322T, I329L  
>ZZR48| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFCEVQLGIPHPSGLKKKKSATVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPELVI
YQYVDDLYVASDLEIGQHRAKVEELRQHLLKWGLFTPDQKYQKEPPLLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAELQKQG

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009