<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215TNSY F77FL K101P, Y181YC   V35T, E36A, T39K, K43E, K122E, D123S, I135T, T139R, I142V, S162A, K173S, Q174K, D177E, V179I, T200A, Q207A, R211T, V245Q, S251H, A272G, T286A, E291D, V292I, I293V, P294T, E312D, I326V  
>ZZR160| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDLRELNKRTQDFWEVQLGIPHPAGLPKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNERPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRSKNPEIII
CQYVDDLYVGSDLEIGQHRAKIEELRAHLLTWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDHWTVNDIQKLVGKLNWASQIYGGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, E35D, M36I, R41K, K45R, H69K, L89M  
>ZZR160| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009