Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6589 | CA16432 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 279 |
| 2 | 3TC+D4T+NFV | 48 |
| 3 | 3TC+AZT+IDV | 35 |
| 4 | EFV+RTV+SQV | 37 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W | T215C | K103N | V108I, L234LI | T7P, K20R, V35L, T39K, K43E, K122E, I135T, G196E, T200A, Q278H |
| >CA16432| codons 1-284 PISPIEPVPVKLKPGMDGPRVKQWPLTEEKIKALLEICKELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRAKIEELRQHLWRWGFCTPDKKHQKEPPFLWMGYEIHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLR |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I54V, L90M | L10F, L33I, N88D | K20R, E35D, M36I, R57K, L63P, C67CY, A71AT, I93L |
| >CA16528| codons 1-99 PQITLWQRPFVTIKIGGQLREALLDTGADNTVIEDINLPGRWKPKMIGGIGGFVKVKQYD QIPIEIYGHKTIGTVLVGPTPVNIIGRDLMTQLGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |