<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|TDF|NVP|EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V K219KE Y181C, M230L A98G, V108I, V179E P4S, V8I, K20R, V35T, T39N, E40D, K46KQ, V60I, S68SG, K104R, I135V, K173T, Q174R, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, Q278H, L279I, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329V  
>ZZR127| codons 1-333
PISSIETIPVKLKPGMDGPRVKQWPLTEEKIKALTEICNDMEKEGQISKIGPENPYNTPI
FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKRSVTILDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPDIEI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDEKHQKEPPFLWLGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKHICRLLRGAKALTDIVPLTAEAE
MELAENREILKEPVHGVYYDPSKELIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I13V, I15V, K20I, M36I, N37D, R41K, I62V, I64M, C67S, H69K, V82I, L89M  
>ZZR127| codons 1-99
PQITLWQRPLVPVKVGGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QVLMEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009