<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215FY   K101E, G190A A98G E28K, V35T, V60I, K173T, Q174K, D177E, I178M, T200A, Q207D, V245Q, S251N, A272S, T286A, E291D, V292I, I293V, K311R, E312K, D324E, I329V  
>ZZQ949| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYVDDLYVASDLEIGQHRAKIEELRDHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILRKPVHGVYYDPSKELIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35D, M36I, N37NK, R41H, D60E, L63P, H69K, L89M  
>ZZQ949| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDIKLPGHWKPKMIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009