<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20I, M36I, R41K, C67S, H69K, V82I, L89M  
>ZZQ969| codons 1-99
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y   Y181C A98G, V179E K20R, V35T, T39K, K103R, K122E, K173T, Q174K, D177E, E194D, G196E, T200A, Q207E, R211K, H221HY, P243S, V245Q, E248D, D250E, S251N, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297T, L301M, I329V  
>ZZQ969| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKRKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIEI
CQYVDDLYVGSDLDIEQHRAKIEELREHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQSIQLPDKENWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGAKALTDIVPLTTEAE
MELAENREILKEPVHGVYYDPSKDLIAEVQKQG

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009