Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| R51 | ZZR51 | Nigeria | 2007 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+TDF+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, K20I, M36I, R41K, L63T, I64M, H69K, L89M |
| >ZZR51| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, M184V | Y181C, G190GA | I31IL, V35T, T39M, K122P, I135V, S162A, K173T, Q174EK, D177E, V179IM, T200A, R211K, V245Q, E248D, A272P, K275KR, E291D, V292I, I293V, S322A, A327G |
| >ZZR51| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTEICMEMEKEGKISKIGPENPYNTPV FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIMI CQYVDDLYVASDLEIGQHRAKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPAKDLIGEIQKQG |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |