<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R V75VA, K219E Y181C, M230L   K20R, V35T, V60I, S68G, K104R, K122E, D123N, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, F214L, H221Y, L228R, V245Q, E248D, D250E, S251R, A272P, T286A, E291D, V292I, I293V, K311R, I329V K101*Q, P140T
>ZZQ981| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKRKDGTKWRKLADFRELNKRTQDFWEVQLGIPHPAGLQKKRSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETTGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDEKYQKEPPFRWLGYELHPDKWT
VQPIQLPDKERWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M  
>ZZQ981| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009