<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NRTI|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74LV, M184V F116FY, Q151QL G190GA Y181YFHL E6EDKN, K11KT, P14PS, I31L, V35IT, E36EA, E40EA, K43KE, K66R, S68G, A98S, K102KQ, K122KE, D123DE, I142IV, S162A, F171FY, Q174E, D177DE, V179VA, T200A, Q207ADE, H208HY, L210LV, H221HY, V245EQ, S251SDGN, K275KQ, K277KR, T286A, E291D, V292I, I293V, P294T, I326IV K173K*ST
>ZZQ964| codons 1-334
PISPINTVPVTLKSGMDGPKVKQWPLTEEKLKALTAICTAMEEEGKISKIGPENPYNTPV
FAIKKRDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKQKKSVTVLDVGDAYYSVPL
DEEFRKYTAFTIPSINNETPGVRYQYNVLPLGWKGSPAIFQASMTKILEPYRTENPEIAI
LQYVDDLYVASDLEIGQHRAKIEELREYLVRWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10IV, I13V, L19LPS, K20KI, E35D, M36I, N37NS, R41K, R57RK, L63LV, K70KR, L89M  
>ZZQ964| codons 1-99
PQITLWQRPVVTVKIGGQSIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVKQYD
QIVIEICGHRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009