<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|TDF|NVP|EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184I   K103N, Y181C, M230L   V35T, E36D, S68G, T69N, V90I, D123E, I135T, I142V, S162A, K173I, Q174K, D177E, T200A, Q207E, E224N, L228R, P243T, V245Q, E248EDKN, K249KQ, S251C, A272P, L283I, T286V, E291D, V292I, I293V, P294T, L295M, S322T K220NS, H221I, Q222R
>ZZQ774| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV
FAIKRKDGNKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPEIVI
CQYIDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKSIRKNPPFRWLGYELHPDKWT
VQTIQLPNQDCWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGVKALTDIVTMTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, M36I, R41K, H69K, P79D, L89M  
>ZZQ774| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGDTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009