<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219Q K103N A98G K32R, V35T, V60I, K122E, D123N, I135M, E138Q, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, I244V, V245K, D250DE, Q278QH, T286A, E291D, I293V, P294T, L295M, S322T, I326V  
>ZZQ735| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSMNNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPELVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTPDQKHQKEPPFLWMGYELHPDKWT
VQPVKLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTDVVTMTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, L19P, K20I, E35D, M36I, R41K, H69K, L89M L63HY
>ZZQ735| codons 1-99
PQITLWQRPIVTVRIGGQPIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIYIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009