<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP|EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13A, K14KR, I15IV, K20I, M36I, R41K, K43R, L63PS, H69K, L89I  
>ZZQ142| codons 1-99
PQITLWQRPLVAARVGGQLIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       E28EA, V35T, I135V, S162A, K173AT, Q174K, D177E, I178M, T200A, Q207E, R211K, V245NS, A272P, L283I, T286A, I293V, P294T, E312EG, S322A, I326V  
>ZZQ142| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPISLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGAKALTEVVTLTEEAE
LELAENREILKGPVHGVYYDPAKDLVAEIQKQGQ

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009