<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20I, M36I, R41K, C67N, H69K, K70R, V82I, L89M  
>ZZQ407| codons 1-99
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEINGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, T69~, Q151M V75I, F77L, K219R K103N, Y181V   K20R, V35T, T39K, V60I, S68G, K101R, V111I, D121Y, K122E, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, V245Q, E248N, D250E, S251D, A272P, T286A, A288S, E291D, V292I, I293V, E297T, L301M R83I, H96L, K126N
>ZZQ407| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPI
FAIKRKDG~KWRKLIDLRELNKITQDFWEVQLGIPLPAGLRKNKSVTVLDIGDAYFSVPL
YEDFRNYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPYRTKNPEMVI
VQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDRKYQKEPPFLWMGYELHPDKWT
VQPIQLPNKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKSLTDIVPLTTEAE
MELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009