Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, V11A, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69R, V82I, L89M |
| >ZZQ240| codons 1-99 PQITLWQRPIATVRIGGQLIEALLDTGADDTVLEQIDLPGKWKPKMIGGIGGFIKVKQYD QILIEIEGRKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106VA, Y181YC, Y188YC | V35IT, E36EA, T39DEKN, K122E, D123S, I135T, K173AT, Q174K, I178M, T200A, Q207E, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, P294T, P321S, D324E, I329V |
| >ZZQ240| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICNEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDMVI CQYMDDLCVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIITLTEEAE LELAENREILKEPVHGVYYDSSKELIAEVQKQG |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |