<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69D       V35T, E40A, K43E, K49R, V60I, V106I, V118I, K122KE, T139S, T165I, N175H, D177E, I178L, Q197E, E203D, E204R, Q207D, R211K, F214L, E224D, V245T, E248Q, A272P, K275R, K277KR, V292I, I293V, I329V, Q334E  
>ZZQ234| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTAMEEEGKISRIGPENPYNTPI
FAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNESPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQHPELVI
YQYMDDLYVGSDLEIGEHRTKIDRLRDHLLKWGLTTPDKKHQKDPPFLWMGYELHPDKWT
VQPITLPQKDSWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLLRGTKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGEG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, K20R, E35D, M36I, R41K, R57RK  
>ZZQ234| codons 1-99
PQITLWQRPLVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009