Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Q223 | ZZQ223 | Nigeria | 2007 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K219Q | Y181C | A98G | K20KR, V21VI, V35T, E40D, K49R, V60I, T69N, K122E, D123NS, I135T, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, F214L, D218E, L228H, V245KLMQ, E248D, D250K, A272P, T286A, E291D, V292VI, I293V, K311KR, I329V |
| >ZZQ223| codons 1-333 PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI CQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGLTTPEQKHQKEPPFHWMGYELHPDKWT VQPIQLPDKKSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILREPVHGVYYDPSKDLIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35Q, M36I, N37D, R41K, L63P, C67E, H69K, V82I, L89M |
| >ZZQ223| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEQIDLPGKWKPKMIGGIGGFIKVRQYD QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |