<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KE, M184V, T215TFIS V75VA, F116FY Y188L   V35T, E36EK, V60I, K104KQ, L109LI, D123E, I135L, S162A, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, D218DE, V245E, V276I, K277R, L283I, T286A, E291D, I293V, P294T, V317A, S322T K73LQ
>ZZQ209| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTKICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTEWRQLADFRELNKRTQDFWEVQLGIPHPAGLKKKQSVTVIDVGDAYYSVPL
DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPELVI
YQYVDDLLVGSDLEIGQHRAKIEELREHLLKWGFSTPEKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIRQLCKLIRGAKALTDVVTLTEEAE
LELAENREILKEPVHGAYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10IV, I13V, L19P, K20I, M36I, R41K, L63PS, H69K, I72IT, L89M  
>ZZQ209| codons 1-99
PQITLWQRPVVTVKIGGQPIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QISIEICGKKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009