<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, M184V   Y181YC, G190GA V108I V35T, T39N, E40D, V60I, K104R, K122E, D123N, I135IT, K173T, Q174K, D177E, I178M, T200A, E203EK, Q207E, R211K, H221Y, V245Q, E248NS, D250E, A272P, T286A, E291D, V292I, I293V, I329V  
>ZZQ191| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNDMEKEGKISKIGPENPYNTPI
FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTILDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
CQYVDDLYVASDLEIGQHRAKIKELREHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPSKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, Q18K, K20I, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89M E35H
>ZZQ191| codons 1-99
PQITLWQRPLVTVRIGGKLIEALLDTGADDTVLEHIDLPGKWKPKMIGGIGGFIKVKQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009