<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, T69TADN, K70R, M184V V75I, K219Q Y181C A98G K20R, V35T, T39K, E40D, V60I, K104R, K122E, D123E, I132L, I135T, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, H221HY, L228LH, V245Q, E248D, D250E, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, I329V  
>ZZP660| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKDMEKEGKISKIGPENPYNTPI
FAIKKKNSNRWRKLIDFRELNKRTQDFWEVQLGIPHPGGLKKKRSVTVLDVGDAYFSVPL
DEEFRKYTAFTLPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDQKYQKEPPFHWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTDIVPLTAEAE
MELAENREILKEPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, K20I, M36I, R41K, L63LP, C67S, H69K, V82I, L89M  
>ZZP660| codons 1-99
PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009