Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | K101E, Y181C | V108I | V21I, V35T, V60I, K104R, K122E, D123S, I135RT, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, H221Y, V245Q, E248D, D250E, A272S, K277R, T286A, E291D, V292I, I293V, P294Q |
| >ZZP609| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKRSVTILDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPELVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVQLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LI, I13V, K14KR, I15IV, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M |
| >ZZP609| codons 1-99 PQITLWQRPIVTVRVGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |