<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219EQ Y181C A98G K20R, V35T, T39E, E40D, V60I, V106I, I135T, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, H221HY, V245K, E248D, D250E, A272PS, I274V, K275KR, Q278N, T286A, E291D, V292I, I293V, P294T, E297V, L301M, E312G, I329V  
>ZZP895| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEDMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSITVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
CQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDQKYQKEPPFLWMGYELHPDKWT
VQPIKLPDKESWTVNDIQKLVGKLNWASQIYSGVRVKNLCKLLRGAKALTDIVTLTVEAE
MELAENREILKGPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90LM   I13V, K20I, E35D, M36I, R41K, L63P, C67GS, H69K, V82I, L89M  
>ZZP895| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEISGKKAIGTVLVGPTPINIIGRNMMTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009