<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219Q Y188L A98G K20R, V35T, T39Q, E40ED, V60VI, L109I, V118VI, K122E, D123N, K166R, F171Y, K173T, Q174E, D177E, I178M, T200A, I202V, E204EK, Q207E, F214L, V245Q, D250E, S251A, A272P, I274V, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, E297P, L301M, I329V  
>ZZP655| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICQDMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVIDVGDAYFSIPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPYRTENPEMVI
YQYVDDLLVGSDLEIGQHRAKVEKLREHLLRWGLFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKEAWTVNDIQKLVGKLNWASQIYPGVKVRHLCRLLRGAKALTDIVTLTPEAE
MELAENREILKEPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, M36I, R41K, C67S, H69K, V82I, L89M  
>ZZP655| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEISGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009