<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
P625 ZZP625 Nigeria 2007 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, R41K, R57K, L63T, I64L, H69K, K70KR, I72T, V82VI, L89M  
>ZZP625| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QITLEICGKRATGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, M184V, L210LW, T215F K219K*RW K101E, Y181V   E28K, V35T, K49KR, V60I, T69TN, V118VI, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, L228LR, V245E, D250E, A272T, T286TP, E291D, I293V, V317VA K32K*E, E36E*
>ZZP625| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALT*ICTELEKEGKISRIGPENPYNTPI
FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIII
VQYVDDLYVGSDLEIGQHRTKIEELRAHLWSWGFFTPDWKHQKEPPFRWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGPKALTDVVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009