Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| P625 | ZZP625 | Nigeria | 2007 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, R57K, L63T, I64L, H69K, K70KR, I72T, V82VI, L89M |
| >ZZP625| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QITLEICGKRATGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V, L210LW, T215F | K219K*RW | K101E, Y181V | E28K, V35T, K49KR, V60I, T69TN, V118VI, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, L228LR, V245E, D250E, A272T, T286TP, E291D, I293V, V317VA | K32K*E, E36E* |
| >ZZP625| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALT*ICTELEKEGKISRIGPENPYNTPI FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIII VQYVDDLYVGSDLEIGQHRTKIEELRAHLWSWGFFTPDWKHQKEPPFRWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGPKALTDVVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Hawkins, CA | Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. | JAIDS, 2009 |