<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Y115F, M184V A62AV, V75I V106A, Y181C   K20R, V21I, V35T, E36D, V60VI, V90I, D121H, K122E, D123E, I135V, S162A, K173T, Q174K, D177E, I178IM, T200A, Q207E, R211K, H221Y, P243T, V245Q, K277Q, T286A, E291D, I293V, E297R, S322T, I326V  
>ZZP614| codons 1-334
PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPI
FVIKKKDSTKWRKLIDFRELNKRTQDFWEIQLGIPHPAGLKKKKSATVLDVGDAFFSVPL
HEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVQQLCKLLRGAKALTDVVPLTREAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G16E, K20I, M36I, R41K, K43KR, H69K, L89M  
>ZZP614| codons 1-99
PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009