<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V K219KQ Y181C V108I V35T, E40D, K122E, D123N, K166KR, K173A, Q174K, D177E, I195T, T200A, Q207D, L228R, V245Q, E248D, D250T, S251V, K281KR, L283I, T286AV, E291D, V292I, I293V, I326V E203EAKT
>ZZP612| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPV
FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI
CQYVDDLYVGSDLETGQHRAKITELRDHLLRWGFTTPDQKHQKEPPFRWMGYELHPDKWT
VQPIQLPDKTVWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLIRGVKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L   I13V, K20I, E35Q, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M  
>ZZP612| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPKLIGGIGGFIKVKQYD
QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009