<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, V75VAIT, M184V, T215TFIS A62AV Y181C   I31IL, V35I, E53D, T69N, I135L, S162A, K173T, Q174N, D177E, I178M, G196E, T200A, Q207E, H221HY, L228LR, P243S, V245E, K249KR, K277R, T286A, E291D, V292I, I293V, P294T, E297K, S322T  
>ZZP610| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALIEICTEMEKEGKISKIGPDNPYNTPV
FVIKKKDSNRWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTNNPEMVI
CQYVDDLYVGSDLEIEQHRAKIEELREHLLRWGFSTPDKKYQKEPPFRWMGYELHPDKWT
VQSIELPERDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTKEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K14R, I15V, K20I, M36I, N37T, R41K, L63LF, H69K, K70KR, L89M  
>ZZP610| codons 1-99
PQITLWQRPVVTVRVGGQLIEALLDTGADDTVLEEITLPGKWKPKMIGGIGGFIKVRQYD
QIFIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hawkins, CA Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. JAIDS, 2009