<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, V31I, V37I, T112M, T124A, T125A, K136Q, V201I, T218I, L234V, S255R, D256E S283G
>ES| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPIVAKEIIASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKMIHTDNGSN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNREIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, G16E, E35D, M36I, P39S, R41K, R57K, L63T, E65D, K70R, L89M  
>ES| codons 1-99
PQITLWQRPVVTIKVEGQLKEALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVKQYD
QITIDICGHRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, D123E, T139K, S162C, K173I, Q174K, T200E, Q207N, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, V317A, A327V, R356K, R358K, G359S, T377L, K431T, V435A, E449D, L452K, V466A, D471E, T477A, L491P, S519N, K527Q, E529T, K530R, V531I, A534S, V559I  
>ES| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRIKNPDIVI
YQYMDDLYVGSDLEIGQHREKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGAYYDPSKDLIVEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMKSA
HTNDVKQLTEAVQKIALESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGAETFYVDGAANRDTKKGKAGYVTDRGRQKAVSLTETTNQKAELQ
AIHLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIQKTRIYLSWVPAHK
GIGGNEQVDKLVSAGIRKIL

References
Author Title Citation
Fernandez-Garci­a, A Near full-length genome characterization of a newly identified HIV type 1 subtype F variant circulating in St. Petersburg, Russia. ARHR, 2009