<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T215Y   K103N, Y181C, G190A A98G K32N, K122E, D123E, I135K, I178L, R211K  
>BRGO3125| codons 1-245
PISPIETVPVKLKPGMDGPKVKQWPLTEEKINALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI
CQYMDDLYVASDLEIGQHRTKIEELRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L10F, L24I T12P, L19I, K20M, E35D, M36I, R41K, L63P, A71T, I93L  
>BRGO3125| codons 1-99
PQITLWQRPFVPIKIGGQIMEALIDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYD
QIPIEICGHKTIGTVLVGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Cardoso, LP High level of multidrug resistance mutations in HIV type 1 pol gene and resistance-associated mutations to enfuvirtide (T-20) among antiretroviral-experienced patients from central Brazil. ARHR, 2009