<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G16E, E35D, M36I, R41K, K43R, L63V, G68E, H69K, K70R, L89I, T91V, I93L  
>01CM.1445MV| codons 1-99
PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYD
QIVIEICEKRAIGTVLVGPTPVNIIGRNILVQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39K, E40D, D121Y, K122E, I142V, T165I, K173T, Q174K, D177E, V179I, T200A, Q207A, V245K, K275Q, K281R, T286A, E291D, V292I, I293V, E297R, A304E, E312N, I326T, G335D, R356K, M357K, G359T, A360T, A376V, T377M, K390R, A400T, K431Q, V466I, D471E, K476R, Q480H, H483Y, L491S, K512R, S519N, Q524E, K530R, V531I, A534S, A554S  
>01CM.1445MV| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMIKILEPFRTKNPEIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIQVKQLCRLLRGAKALTDIVPLTREAE
LELEENREILKNPVHGVYYDPSKDLTAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRTT
HTNDVKQLTEAVQKIVMESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEQEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKIVSLTETTNQRTELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEELIKKERIYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S24H, V31I, M50I, I72V, L101I, T112V, S119P, T124A, I135V, K136Q, G193D, V201I, K215R, D232E, L234I, A265V S283G
>01CM.1445MV| codons 1-288
FLDGIDKAQEEHERYHSNWRAMAHDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN
FTSATVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGDYSAGERIIDIIATDIQTKELQRQITKIQNFRVYYRDSREPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Carr, JK HIV-1 recombinants with multiple parental strains in low-prevalence, remote regions of Cameroon: Evolutionary relics?. Retrovirology, 2010