<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, E13D, A21T, V31I, I72V, L74I, I84M, P90S, T112V, T124A, K136Q, D167E, V201I, K219N, N222K, L234I S283G
>01CM.4038STN| codons 1-288
FLDGIDKAQEDHDKYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYMEAEVISAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSATVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITNIQKFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20R, E35G, M36I, R41K, R57K, L63V, I64M, H69K, L89M  
>01CM.4038STN| codons 1-99
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEGINLPGKWKPKMIGGIGGFIKVKQYD
QIVMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6K, V35T, T39R, K122E, D123S, I135T, K173S, D177E, T200A, Q207A, F214L, V245L, A272P, K275R, T286A, E291D, V292I, I293V, P294T, E312D, S322L, D324E, I326V, G335D, I341L, M357K, G359S, A360T, K366R, T369V, A371V, I375V, A376T, T386I, A400T, T403A, E432D, D471E, H483Y, L491S, K512S, S519N, Q524K, K527G, A534S  
>01CM.4038STN| codons 1-560
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPLKELVAEIQKQGQDQWTYQLYQEPFKNLKTGKYARKRST
HTNDVRQLVEVVQKVTTESIVIWGKIPKFKLPIQKETWETWWAEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELQ
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDSSESELVNQIIEKLIGKEKVYLSWVPAHK
GIGGNEQVDKLVSAGIRKVL

References
Author Title Citation
Carr, JK HIV-1 recombinants with multiple parental strains in low-prevalence, remote regions of Cameroon: Evolutionary relics?. Retrovirology, 2010