<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 D4T+3TC+EFV 56

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215F   K103N P225H I31L, V35T, T39N, D121Y, K122E, D123E, I142V, S162C, D177E, I178L, Q207E, R211K  
>BV147-1| codons 19-234
PKVKQWPLTEEKLKALTEICNEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFR
ELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPLYEEFRKYTAFTIPSINNE
TPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPELVIYQYVDDLYVGSDLEIGQH
RTKIEELREHLLKWGFFTPDKKHQKEHPFLWMGYEL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, I13V, G16E, E35D, M36I, R41K, L63V, G68E, H69K, K70R, L89M, T91V, I93L  
>BV147-2| codons 1-99
PQITLWQRPIVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIVIEICEKRAIGTVLVGPTPVNIIGRNMLVQLGCTLNF

References
Author Title Citation
Steegen, K Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya. AIDS Res Ther, 2009