<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 D4T+3TC+EFV 141

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N V108I V35T, V60I, K102Q, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, I178M, Q207T, R211S  
>BV145-2| codons 23-230
QWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNK
RTQDFWEVQLGIPHPAGLKQNKSVTILDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGV
RYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEMVIYQYVDDLYVGSDLEIGQHRTKI
EELRTHLLSWGFTTPDKKHQKEPPFLWM

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, R41K, R57K, Q61E, L63M, H69K, L89M  
>BV145-1| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
EIMIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Steegen, K Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya. AIDS Res Ther, 2009