<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 D4T+3TC+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V V75I Y181C, G190A   V35T, V60I, D121H, K122E, I132L, I135T, I142IV, S162C, K173L, Q174K, Q207A, R211S  
>BV264-2| codons 20-228
KVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPIFAIKRKDSTKWRKLIDFRE
LNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTLPSTNNET
PGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRLKNPDIVICQYVDDLYVASDLEIGQHR
TKIEELRAHLLSWGFTTPDKKHQKEPPFL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15V, K20KR, E35D, M36I, R41K, R57K, D60DE, H69K, L89M  
>BV264-1| codons 1-99
PQITLWQRPLVTVRVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Steegen, K Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya. AIDS Res Ther, 2009