<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 D4T+3TC+NVP 42

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M, M184V   Y188L, G190A   V35T, V60I, T69TN, D121H, K122E, D123DE, F171Y, K173S, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, F214L  
>BV133-2| codons 24-229
WPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPIFAIKKKDSNKWRKLVDFRELNKR
TQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLHEEFRKYTAFTIPSINNETPGIR
YQYNVLPMGWKGSPAIFQSSMTKILEPYRSKNPEMIIYQYVDDLLVASDLEIGQHRAKIE
ELRAHLLSWGLTTPDKKHQKEPPFLW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12I, I13V, G16E, E35D, M36I, R41K, R57K, H69K, L89M  
>BV133-1| codons 1-99
PQITLWQRPVVIVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Steegen, K Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya. AIDS Res Ther, 2009