<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, L74LI, M184V   K103N, V106M   S48T, V60I, K122E, D123S, I132L, K173A, D177E, T200A, Q207G, R211K, V245Q P226H
>MD0131252006| codons 38-247
CTEMEKEGKITKIGPENPYNTPIFAIKRKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSMTVLDVGDAYFSVPLDESFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTP
DKKHQKEPHFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, L89M, I93L  
>MD0131252006| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Orrell, C HIV type-1 clade C resistance genotypes in treatment-naive patients and after first virological failure in a large community antiretroviral therapy programme. Antivir Ther, 2009