Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4450 | CA16232 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 261 |
| 2 | 3TC+AZT+IDV | 19 |
| 3 | D4T+DDI+NFV+NVP | 21 |
| 4 | 3TC+D4T+DDI+NFV+NVP | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46ML | L33LF | I62V, L63A |
| >CA16232| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADNTVFEEMNLPGRWKPKLIGGIGGFIKVRQYD QVAIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | D67G, K70R_N, K219Q | K11R, K20R, V35I, K49R, K64N, S68Y, D123DN, I135T, T165I, D177E, I195L, F214L, D218E, V245T, K277R, Q278H, A288S, I293V, P294PT, E297K |
| >CA15970| codons 1-299 PISPIETVPVRLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISRIGPENPYNTPV FAINKKGYTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEIVI YQYVDDLYVGSDLELGQHRTKIEELRQHLLRWGLTTPEQKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGTKSLTEVVTLTKEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |