Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA2206 | CA16228 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV | 52 |
| 2 | 3TC+AZT+IDV | 135 |
| 3 | 3TC+D4T+EFV+NFV | 71 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | G73C | L10I, L24M, N37H, I62V, L63P, I64V, T74S, V77I, I85V, I93L |
| >CA16228| codons 1-99 PQITLWQRPIVTIKIGGQLKEALMDTGADDTVLEEMHLPGRWKPKIIGGIGGFIKVRQYD QVPVEICGHKAICSVLIGPTPVNVVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74LV, M184V, L210W, T215Y | K103KN, G190GS | K101HQ | E6EK, K43Q, E44D, V60I, V118I, K122E, I135T, R211K, A272P, Q278H, I293V |
| >CA15966| codons 1-303 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPI FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLHKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVSSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGTKALTEVVPLTEEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |