Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4519 | CA16206 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
| 2 | 3TC+AZT+IDV | NA |
| 3 | 3TC+AZT | 60 |
| 4 | 3TC+D4T+NFV | 104 |
| 5 | Unknown | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, L90M | F53FL, N88D | L10V, I15V, K20KR, E34ED, E35ED, M36I, N37D, K45KR, L63P, A71T, I72V | Q92S |
| >CA16206| codons 1-99 PQITLWQRPVVTIKVGGQLREALLDTGADNTVLDDIDLPGRWKPRMIGGIGGLIKVRQYD QIPIEICGHKTVGTVLVGPTPVNIIGRDLMTSIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | V35VI, T39A, S68G, K122KE, Q174R, Q207R, R211K, S251I, V292I, I293V, E297A |
| >CA15944| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRRHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDIWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEIVPLTAEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |