Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1449 | CA16101 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 55 |
| 2 | ABC+ADV+EFV | 23 |
| 3 | ADV+EFV+NFV | 21 |
| 4 | EFV+IDV+NFV | 4 |
| 5 | 3TC+IDV+SQV | 49 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, L90LM | N88D | I15V, E35D, M36V, N37E, I62V, L63P |
| >CA16101| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADNTVLEDVELPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRDLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210LW, T215Y | A62AV | K20R, I31IL, T39TA, K43KN, L74X, K122E, R211K, A272AP, K275KN | N265NS |
| >CA15838| codons 1-277 PISPIETVPVKLKPGMDGPRVKQWPLTEEKLKALVEICAELENEGKISKIGPENPYNTPV FVIKKKDSTKWRKXVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLSWASQIYPGINVK |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |