Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6495 | CA16029 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 122 |
| 2 | DDI | 26 |
| 3 | 3TC+D4T | 39 |
| 4 | 3TC+DDC+IDV | 126 |
| 5 | 3TC+DDC+NFV | 34 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, M184V | K219Q | K20R, T39A, K82KR, I135V, E169D, Q174N, F214L, L228H, A272P, I293V, T296S, K311R, D324E, G333E, Q334H, R356K, M357I, A360T, T369A, K374R, A376N, E404D, L469I, T470P, D471DE, K476KR, S519N, A554T | I309IT |
| >CA16029| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKNNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLSEEAE LELAENRETLREPVHGVYYDPSKELIAEIQKQEHGQWTYQIYQEPFKNLKTGKYAKIRGT HTNDVKQLAEAVQRINTESIVIWGKTPKFKLPIQKETWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSIPETTNQRTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | I13V, K14R, N37D, L63P, A71AV |
| >CA16292| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADNTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |