<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I15V, L19T, E35D, M36L, R41K, K45R, D60E, I62IV, H69Q, V77VI, L89M, I93L  
>CP076300539| codons 1-99
PQITLWQRPIVTIKVGGQTKEALLDTGADDTVLEDLNLPGKWKPRMIGGIGGFIKVRQYE
QVLIEICGQKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181YC   K20KR, K22KR, V35T, E36A, T39E, S48T, W88C, V90VI, K122E, D123N, T139A, E169ED, D177DE, T200A, E204K, Q207E, F214L, V245Q, A272P, K275R, K277R, Q278QH, E291D, V292I, I293V  
>CP076300539| codons 1-322
PISPIETVPVKLKPGMDGPRVRQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEIVI
CQYMDDLYVGSDLEIGQHRAKIEKLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPS

References
Author Title Citation
Hamers, RL HIV-1 drug resistance mutations are present in six percent of persons initiating antiretroviral therapy in Lusaka, Zambia. JAIDS, 2010
Hamers, RL HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: A multicentre observational study. Lancet, 2011