Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6483 | CA16011 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 69 |
| 2 | D4T+DDI+NVP | 39 |
| 3 | D4T+DDI+NFV | 21 |
| 4 | DDC+RTV+SQV | 48 |
| 5 | ABC+APV+EFV+RTV | 46 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, L210W, T215Y | K219KN | L100I, K103N | V60I, V118I, I135T, K173E, R211K, H221Y, D250E, Q278H, I293V, P294A |
| >CA16011| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFREQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDNKYQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGTKALTEVVALTEEAE LEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54L, I84V, L90M | L33F, N88D | L10V, I13V, E34K, R41K, D60DE, L63P, V77I |
| >CA16273| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVFKEMNLPGKWKPKLIGGIGGFLKVRQYE QIPIEICGHKAIGTVLIGPTPVNVIGRDLMTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |