<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19T, E35D, M36I, R41K, K45R, R57RK, D60E, Q61E, L63S, H69K, L89I, I93L  
>CP076300455| codons 1-99
PQITLWQRPLVTIKVGGQTKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYE
EISIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    G190GA   P4S, V35T, T39E, S48T, V60I, V118I, K122E, D123N, I135T, T139V, K173T, Q174R, T200A, I202V, Q207QELV, R211K, F214L, A272P, T286A, E291D, V292I, I293V, P294T  
>CP076300455| codons 1-324
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSTNNEVPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPDIVI
YQYMDDLYVASDLEIGQHRAKVEELRVHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKD

References
Author Title Citation
Hamers, RL HIV-1 drug resistance mutations are present in six percent of persons initiating antiretroviral therapy in Lusaka, Zambia. JAIDS, 2010
Hamers, RL HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: A multicentre observational study. Lancet, 2011