Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6423 | CA15929 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 74 |
| 2 | D4T+NFV+NVP | 57 |
| 3 | ABC+AZT+EFV+RTV+SQV | 60 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L74V, T215F | K103N, Y181C, G190A | P1L, I31L, V35L, K122E, D123N, R211K, L228H, T286A | K281KE |
| >CA15929| codons 1-303 LISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALLEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVASDLEIGQHRTKIEELRQHLLKWGFFTPDKKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCELLRGAKALTEVIPLTEEAE LEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46I, I54V | F53L, N88D | L10I, I13V, K20R, E35D, M36I, L63P, A71T, I93L |
| >CA16197| codons 1-99 PQITLWQRPIVTVKIGGQLREALLDTGADNTVLEDINLPGRWKPKIIGGIGGLVKVRQYD QIPIEICGHKTIGTVLVGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |