Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6409 | CA15910 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 92 |
| 2 | None | 96 |
| 3 | D4T+NFV+NVP | 96 |
| 4 | ABC+APV | 25 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | K101E, Y181YC | E138EK | K20R, T39A, T69N, K122E, A158AT, I202V, L228LR, V245IM, R284K, A288T, I293V |
| >CA15910| codons 1-303 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPTIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRTKVEELRQHLLRWGFFTPDQKHQKEPPFRWMGYELHPDKWT VQPIILPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKTLTEVVPLTEEAE LEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L33LF, G73S | L10I, K20T, E35D, M36I, N37E, I62V, L63P, A71V |
| >CA16172| codons 10-99 IVTIKIGGQLTEALLDTGADDTVFEDIELPGRWKPKMIGGIGGFIKVRQYDQVPIEICGH KVISTVLVGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |